Wistar Institute

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Engraving on the original building reads Wistar Institute of Anatomy
Engraving on the original building reads Wistar Institute of Anatomy
Expanded research facilities are visible from the south
Expanded research facilities are visible from the south

The Wistar Institute, an independent nonprofit biomedical research institute in Philadelphia, Pennsylvania, United States, is dedicated to discovering the causes and cures for major diseases, including cancer, cardiovascular disease, autoimmune disorders, and infectious diseases. The institute is located on the campus of the University of Pennsylvania. Founded in 1892 as the first institution of its kind in the nation, The Wistar Institute today is a National Cancer Institute-designated Cancer Center focused on basic and translational research. Discoveries at Wistar have led to the development of vaccines for such diseases as rabies, rubella, and rotavirus, the identification of genes associated with breast, lung, and prostate cancer, and the development of monoclonal antibodies and other significant research technologies and tools. The Institute works actively to transfer its inventions to the commercial sector to ensure that research advances with the potential to benefit public health move from the laboratory to the clinic as expeditiously as possible.

The oral polio vaccine CHAT, used by Hilary Koprowski in Africa and the focus of the OPV AIDS hypothesis, was developed at the Wistar Institute.

Wistar Rats, one of the most popular rat strains for laboratory research, are descended from a colony established at the Wistar Institute in 1906.

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