VAMP

From Wikipedia, the free encyclopedia

Vesicle associated membrane protein (VAMP) family of proteins includes proteins with similar structure.

  • VAMP-3 (known as cellubrevin) is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles.
  • VAMP-5 and VAMP-7 participate in constitutive exocytosis. VAMP-5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures, while VAMP-7 is found both in secretory granules and endosomes.
  • VAMP8 (known as endobrevin) participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells.

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