Tropane

From Wikipedia, the free encyclopedia

Tropane[1]
IUPAC name 8-Methyl-8-azabicyclo[3.2.1]octane
Other names 2,3-Dihydro-8-methylnortropidine
Identifiers
CAS number [529-17-9]
PubChem 637986
SMILES CN1C2CCC1CCC2
Properties
Molecular formula C8H15N
Molar mass 125.211 g/mol
Density 0.9259 at 15 °C
Boiling point

163-169 °C

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Tropane is a nitrogenous bicyclic organic compound with chemical formula C8H15N. It is mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine. Both alkaloids contain tropinone from which tropane is a derivate. Tropane alkaloids occur in plants of the families Solanaceae (mandrake, henbane, deadly nightshade, Datura species) and Erythroxylaceae (coca).[2][3]

8-Azabicyclo[3.2.1]octane (tropane without the 8-methyl group) is known as nortropane or nor-tropane.

  1. ^ Merck Index, 11th Edition, 9689.
  2. ^ Atropine content of plants. USDA, ARS, National Genetic Resources Program. Phytochemical and Ethnobotanical Databases. [Online Database] National Germplasm Resources Laboratory, Beltsville, Maryland. Retrieved on July 25, 2005.
  3. ^ Cocaine content of plants. USDA, ARS, National Genetic Resources Program. Phytochemical and Ethnobotanical Databases. [Online Database] National Germplasm Resources Laboratory, Beltsville, Maryland. Retrieved on July 25, 2005.


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