Eccrine sweat glands

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A diagrammatic sectional view of the skin (magnified). Sweat gland labeled as "sudoriferous gland" at center right.
A diagrammatic sectional view of the skin (magnified). Sweat gland labeled as "sudoriferous gland" at center right.

Eccrine sweat glands are distributed over the entire body surface but are particularly abundant on the palms of hands, soles of feet, and on the forehead. These produce sweat that is composed chiefly of water with various salts. These glands are used for body temperature regulation.

Eccrine sweat glands are coiled tubular glands derived from the outer layer of skin but extending into the inner layer. They are distributed over almost the entire surface of the body in humans and many other species, but are lacking in some marine and fur-bearing species. The sweat glands are controlled by sympathetic cholinergic nerves which are controlled by a centre in the hypothalamus. The hypothalamus senses core temperature directly, and also has input from temperature receptors in the skin and modifies the sweat output, along with other thermoregulatory processes.

Human eccrine sweat is composed chiefly of water with various salts and organic compounds in solution. It contains minute amounts of fatty materials, urea, and other wastes. The concentration of sodium varies from 35–65 mmol/l and is lower in people accustomed to a hot environment. The sweat of other species generally differ in composition.

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