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Pyrrolidine
From Wikipedia, the free encyclopedia
(Redirected from Tetrahydropyrrole)
| Pyrrolidine | |
|---|---|
 |
 |
| IUPAC name | Pyrrolidine |
| Other names | azacyclopentane tetrahydropyrrole |
| Identifiers | |
| CAS number | |
| PubChem | |
| RTECS number | UX9650000 |
| SMILES | C1CCNC1 |
| Properties | |
| Molecular formula | C4H9N |
| Molar mass | 71.11 |
| Appearance | clear liquid |
| Density | 0.866 |
| Melting point |
-63 |
| Boiling point |
87 |
| Solubility in water | miscible |
| Acidity (pKa) | 11.27 |
| Basicity (pKb) | 2.74 |
| Hazards | |
| Main hazards | highly flammable, harmful, corrosive, mutagen |
| R-phrases | 11 20/21/22 35 |
| S-phrases | 16 26 28 36/37 45 |
| Flash point | 3 |
| Related Compounds | |
| Related compounds | pyrrole piperidine |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
|
Pyrrolidine is an organic compound with the molecular formula C4H9N. It is a cyclic amine with a five-membered ring containing four carbon atoms and one nitrogen atom. It is a clear liquid with an unpleasant ammonia-like odor.
Pyrrolidine is found naturally in the leaves of tobacco and carrot. The pyrrolidine ring structure is present in numerous natural alkaloids such as nicotine and hygrine. It is found in many pharmaceutical drugs such as procyclidine and bepridil. It also forms the basis for the racetam compounds (e.g. piracetam, aniracetam).
A pyrrolidine ring is the central structure of the amino acids proline and hydroxyproline.