Galactosylceramidase
From Wikipedia, the free encyclopedia
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galactosylceramidase
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| Identifiers | |
| Symbol | GALC |
| Entrez | 2581 |
| HUGO | 4115 |
| OMIM | 606890 |
| RefSeq | NM_000153 |
| UniProt | P54803 |
| Other data | |
| EC number | 3.2.1.46 |
| Locus | Chr. 14 q31 |
Galactosylceramidase is an enzyme which removes galactose from ceramide derivatives (galactocerebrosides).
A deficiency is associated with Krabbe disease.
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| 3.2.1: Glycoside hydrolases | Amylase (Alpha-Amylase) - Chitinase - Lysozyme - Neuraminidase - Galactosidases (Alpha, Beta) - alpha-Mannosidase - Glucuronidase - Hyaluronidase - Pullulanase - Glucocerebrosidase - Galactosylceramidase - Alpha-N-acetylglucosaminidase - Fucosidase - Hexosaminidase - Iduronidase - Disaccharidase (Sucrase/Sucrase-isomaltase/Invertase, Maltase, Trehalase, Lactase) - Glucosidases (Cellulase, Alpha-glucosidase, Beta-glucosidase, Debranching enzyme) |
| 3.2.2: Hydrolysing N-Glycosyl compounds | DNA glycosylases: Oxoguanine glycosylase |
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| Arylsulfatase A - Ceramidase - Galactosidases (Alpha, Beta) - Galactosylceramidase - Glucocerebrosidase - Hexosaminidase - Sphingomyelin phosphodiesterase |