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Follicular dendritic cells
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(Redirected from Follicular dendritic cell)
Follicular dendritic cells (FDC) are cells of the immune system found in lymph follicles.[1] They are probably not of hematopoietic origin, but simply look similar to true dendritic cells.[2] They share their appearance and function with the other types of dendritic cells. They are, however, classified differently in MeSH. [3]
They assist in B cell maturation by the presentation of intact antigen to the B cells. This occurs in the germinal centers of peripheral lymphoid organs and induces class switching and proliferation.
- ^ Liu Y, Grouard G, de Bouteiller O, Banchereau J (1996). "Follicular dendritic cells and germinal centers". Int Rev Cytol 166: 139-79. PMID 8881775.
- ^ van Nierop K, de Groot C (2002). "Human follicular dendritic cells: function, origin and development". Semin. Immunol. 14 (4): 251–7. PMID 12163300.
- ^ MeSH Follicular+Dendritic+Cells
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| General | Plasma - Hematopoietic stem cells |
| Lymphoid - WBC | T cells: Cytotoxic CD8+, Helper CD4+/Regulatory, γδ, Natural Killer T cell B cells: Plasma, Memory Natural killer cells (Lymphokine-activated killer cell) |
| Myeloid - WBC | Granulocytes (Neutrophil, Eosinophil, Basophil) - Mast cell precursors Dendritic cells (Langerhans cells, Follicular dendritic cells) Monocytes/Macrophages (Histiocytes, Kupffer cells, Langhans giant cells, Microglia, Osteoclasts) Megakaryoblast - Megakaryocyte - Platelets |
| Myeloid - RBC | Reticulocyte - Normoblast |
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