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Eudoxia Dmitriyevna (Russian: Евдокия Дмитриевна)—monastic name, Euphrosyne— (? - 1407) was a Grand Duchess of Muscovy and wife of Dmitry Donskoy.

Eudoxia Dmitriyevna was a daughter of Dmitry Konstantinovich, Grand Prince of Nizhny Novgorod. In 1366, she married Grand Prince Dmitry Donskoy. In 1382, she stayed in Moscow in the absence of her husband, while the army of khan Tokhtamysh was approaching the capital. After the birth of her son Andrey Dmitriyevich, she attempted to leave Moscow, but was detained by the Muscovites, who agreed to let her go only after long negotiations.

After her husband's death, Eudoxia became known for her pious ways; the legend has it that she possessed the gift of healing. In 1393, she founded the Church of the Nativity of the Theotokos (Церковь Рождества Богородицы), the oldest surviving building in Moscow. The church was dedicated to the Virgin's Nativity, because on this feast her husband defeated the Tatars in the Battle of Kulikovo.

Four years later, Eudoxia established the Ascension Monastery next to the Frolovskaya (Spasskaya) Tower of the Moscow Kremlin. Later in her life, Eudoxia Dmitriyevna took the veil at the Ascension Monastery under the name of Yefrosiniya (Euphrosyne) and remained there until her death in 1407. She was canonized by the Russian Orthodox Church.

On 15 August 2007, the Holy Synod of the Russian Orthodox Church instituted the Order of St. Euphrosyne, named after Eudoxia, who was the first noblewoman of Moscow to enter monasticism. The award was established to commemorate the 600th anniversary of Euphrosyne’s passing away. According to the synod’s ukase (decree), the new decoration will be given to women for special contributions towards the strengthening of spiritual and moral traditions in society, development of the church’s social activities, maintaining relations between church and state or church and society, and other fields of work for the betterment of the Orthodox faith. The Order of St. Euphrosyne will be the second women’s decoration of the Russian Orthodox Church after the Order of St. Olga.^[1]