From Wikipedia, the free encyclopedia

António Caetano de Abreu Freire Egas Moniz (born November 29, 1874, died December 13, 1955), pron. IPA: ['ɛgɐʃ mu'niʃ], was a Portuguese psychiatrist and neurosurgeon. He was the first Portuguese to receive a Nobel Prize, "for his discovery of the therapeutic value of leucotomy in certain psychoses".^[1]

He was born in Avanca, Portugal. He was the inventor of prefrontal leucotomy which was changed to lobotomy by American surgeons who introduced a larger severing of the neural fibres. It was used as a surgical approach to the radical treatment of several kinds of mental diseases; one of the several types of psychosurgery. For this work, Moniz received the Nobel Prize in 1949, jointly with the Swiss neurophysiologist Walter Rudolf Hess.

Contents 1 Career 2 See also 3 References 4 External links

Moniz studied medicine in the University of Coimbra and thereafter psychiatry in Bordeaux and Paris, France. Of special note is that he was not initially a student of neurology as it is nowadays recognised, although psychiatry was not distinct from neurology at this time. He returned to the University of Coimbra as Chairman of the Department of Neurology (1902), but soon left it to enter politics as a representative in the Portuguese parliament (1903-1917), as minister of Foreign Affairs (1918) and later as Ambassador to Spain, under the First Republic (1918-1919). He left politics, returned to the University of Lisbon, where, from 1921 to 1944, he was professor of Neurology. In 1927 he developed cerebral angiography, the technique of using x-rays to visualize arteries and veins that are transiently opacified with the injection of a high density agent. This procedure would allow physicians to map blood vessels in and around the brain, permitting the diagnosis of several kinds of neurological disorders, such as tumors and arteriovenous malformations. He received the Oslo Prize for this discovery. The method is widely used today for the diagnosis of brain tumors and vascular diseases in the brain and other organs. It saved thousands of lives.

In 1936, Egas Moniz and his associate Almeida Lima developed for the first time a surgical technique to interrupt the nerve fibers which connect the thalamus (a relay for sensory information coming into the brain) to the prefrontal cortex (already known at the time as a brain structure involved in higher intellectual functions of the brain, and in emotions, as well). His technique was widely used around the world in the next decade, and Moniz received many honours and international recognition, culminating with the Nobel Prize.

His work also attracted controversy and moral concerns. His surgical approach subsequently fell into disrepute, partly due to Walter Freeman in the US who slightly modified the technique and used it indiscriminately.

Dr. Moniz was shot in 1939 by a psychiatric patient. He survived but was left partially paralyzed.^[2] The patient gave vague reasons for the shooting saying he was unsatisfied with the dose of a drug Dr. Moniz had prescribed. He died in 1955, in Lisbon, Portugal, of natural causes.

His former country house became a museum where one can see his art collection. It can be visited in Avanca, in the north of Portugal. Pictures from the rooms of the museum can be seen at the site http://museuegasmoniz.cm-estarreja.pt

• Nobel Prize controversies
• Psychiatry
• Anti-psychiatry

• The 1949 Nobel Prize in Medicine or Physiology
• Egas Moniz Museum
• The History of Psychosurgery by Renato M.E. Sabbatini
• "Last-Ditch Medical Therapy — Revisiting Lobotomy", Dr. Barron H. Lerner, New England Journal of Medicine, July 14, 2005.
• Psychosurgery.org blog
• Moniz blog by Alvaro Macieira-Coelho

Template:DEFAULT SORT:Moniz, Egas