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DTPA
From Wikipedia, the free encyclopedia
| DTPA | |
|---|---|
 |
|
| General | |
| Systematic name | (Carboxymethyl)iminobis(ethylenenitrilo)]-
tetra-acetic acid |
| Other names | DTPA, Diethylenetriaminepentaacetic acid,
Diethylenetriamine-N,N,N',N',N-pentaacetic acid, N,N-Bis(2-(bis-(carboxymethyl)amino)ethyl)-glycine, Pentetic acid |
| Molecular formula | C14H23N3O10 |
| SMILES | ? |
| Molar mass | 393.3498 g/mol |
| Appearance | White crystalline solid |
| CAS number | [67-43-6] |
| Properties | |
| Density and phase | ? g/cm³, ? |
| Solubility in water | <0.5g/100ml |
| Melting point | 220°C (493.15 K, 428°F) |
| Boiling point | decomposes at a higher temp. |
| Acidity (pKa) | ? |
| Basicity (pKb) | ? |
| Chiral rotation [α]D | ?° |
| Viscosity | ? cP at ?°C |
| Structure | |
| Molecular shape | ? |
| Coordination geometry |
? |
| Crystal structure | ? |
| Dipole moment | ? D |
| Hazards | |
| MSDS | External MSDS |
| Main hazards | ? |
| NFPA 704 | |
| Flash point | Does not burn |
| R/S statement | R: ? S: ? |
| RTECS number | MB8205000 |
| Supplementary data page | |
| Structure and properties |
n, εr, etc. |
| Thermodynamic data |
Phase behaviour Solid, liquid, gas |
| Spectral data | UV, IR, NMR, MS |
| Related compounds | |
| Other anions | ? |
| Other cations | ? |
| Related ? | ? |
| Related compounds | EDTA, NTA |
| Except where noted otherwise, data are given for materials in their standard state (at 25°C, 100 kPa) Infobox disclaimer and references |
|
Diethylene triamine pentaacetic acid (DTPA) is an elongated version of EDTA. It has been used to decontaminate humans who are contaminated with plutonium, americium and other actinides as the compound can chelate these heavy metal ions, render them unabsorbed through the digestive tract and also speeds up the release of these metals in urine. It is normally used as the calcium or zinc salt. It should not be taken by people with kidney disease or bone marrow depression, nor by children younger than 18 years old. If the lungs are contaminated by the inhalation of these radioactive materials, a DTPA spray or mist is used. Otherwise it can also be injected intravenously.
Uses: It is used as a soil extractant for available soil micronutrients like Zn,Fe,Cu and Mn at the pH of 7.3 with Calcium chloride and TEA. Furthermore, it is used as to chelate gadolinium to form a MRI contrast agent, such as Magnevist
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